Natural Cure For Embolism

Final Published Trial Data in The Lancet Supports Safety and Effectiveness of ...

HELPS was a prospective, randomized controlled trial that compared the results from the HydroCoil system to results from bare platinum coils. The 500-patient, independently-run, multicenter, multinational 18-month trial was the first comparative adjudicated study completed since the International Subarachnoid Aneurysm Trial (ISAT) was presented in 2002.  HELPS results were published in the prestigious journal, The Lancet, by the lead author and primary investigator, .  

"Our study shows that the non-invasive techniques for treating brain aneurysms are getting better. Hydrogel coated coils offer an improved treatment for ruptured aneurysms and coiling has a faster recovery than having to have brain surgery and come with less risk as well, which is great news for the thousands of people affected by this condition each year," said Dr. White.

HELPS Trial results showed that the HydroCoil system, based on a microporous expandable hydrogel, proved to be a more stable solution for endovascular occlusion of aneurysms than bare platinum.  The HydroCoil implant is a non-bioactive coil that combines platinum with an expanding hydrogel polymer which provides the features of greater aneurysm volume filling with biologically inert material for natural tissue proliferation.

Angiographic results from an independent core lab indicated there was a statistically significant decrease (8.6%) in major aneurysm recurrence with the HydroCoil system arm as compared to bare platinum control arm.  Aneurysms in the trial ranged in size from 2 mm to 25 mm, and 84% of all aneurysms were medium and large in size.

Natural Course of Treated Pulmonary Embolism ... - Canadian Medicine

, And Vd/ Vt%, even after appropriate treatment, showed the persistence of some abnormalities six months later.

The incomplete recovery of perfusion and of some parameters of gas exchange in pulmonary embolism 180 days later may be due in part to the intrinsically sluggish recovery process and in part to the presence of preexisting conditions such as underlying cardiac or pulmonary diseases. In fact, it is known that the response of the pulmonary vascular system to severe pulmonary emboli with time may differ among individuals in relation to age, smoking habit, his­tory of respiratory symptoms, or the presence of respiratory disease.

In the clinical evaluation of patients with pulmonary embolism, it may be important to follow closely the appearance and the changes in roentgenographic signs with time and their relationships to gas exchange parameters and ULSs. Previous observations have suggested the importance of considering the enlarge­ment of descending pulmonary arteries in screening patients for pulmonary embolism. It has also been suggested to follow the resolution of pulmonary em­bolism from the progressive reduction of the enlarge­ment of the right descending pulmonary artery. canadian antibiotics

Areas of atelectasis, which are evident as densities on the chest x-ray film in pulmonary embolism, have been hypothesized to be the morphologic evi­dence of intrapulmonary shunt. In our study, the occurrence of lung densities was more frequent after one week than at diagnosis, and over one-third of the patients still had densities at one month. We found that patients with lung densities had less impairment of pulmonary gas exchange and fewer ULSs than the other patients at diagnosis. The explanation of this finding could be that the zones of densities may represent areas where both perfusion and ventilation are absent, and thus, they are functionally silent.

In our study the presence of detectable chest x-ray abnormalities was appreciable at up to 30 days of treatment. Thus, the chest roentgenogram appears to be a good tool in giving anatomic information that may be useful for interpreting and, if necessary, in the absence of more specific techniques, substituting perfusion lung scintigraphy and gas exchange meas­urements during the first month of treatment.

In conclusion, perfusion impairment due to pul­monary embolism and its recovery after treatment may be appropriately evaluated by the combined use of perfusion lung scintigraphy, pulmonary gas ex­change, and the chest roentgenogram. In the acute phase of embolization, perfusion lung scintigraphy gives information about the extent of obstruction of the pulmonary vascular bed. This can also be evalu­ated with other simple measurements, such as gas exchange parameters. For the follow-up of these pa­tients, Pa0 st and roentgenographic findings, in addi­tion to perfusion lung scintigraphy, provide all of the anatomic and functional information necessary to evaluate the extent of recovery from pulmonary em­bolism under treatment. Therefore, the three exami­nations should be obtained in all patients during acute embolization and at 7 and 30 days later.

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