New test for Lyme disease in horses and dogs
The new test reveals the infection history and simplifies the testing procedure.The bacteria that causes Lyme disease is Borrelia burgdorferi. It catches a ride with certain species of ticks, and can cause Lyme disease in animals that the ticks bite.
Treating the disease early is paramount because it becomes progressively harder to fight as the bacteria conduct guerilla warfare from hiding places in the joints, nervous tissues and organs of their hosts.
The new test for horses and dogs, developed by researchers at the Animal Health Diagnostic Center (AHDC) at the College of Veterinary Medicine at Cornell, will improve scientists' understanding of the disease and pinpoint the time of infection, opening possibilities for earlier intervention and more effective treatment plans.
"We've offered Lyme disease testing for years," explains lead developer Dr Bettina Wagner, "but we have recently been able to improve our techniques with the multiplex testing procedure.
"The new test exceeds its predecessors in accuracy, specificity, and analytical sensitivity."
The multiplex procedure, which can detect three different antibodies produced in response to the bacteria associated with Lyme disease using a single test on the sample, eliminates the need for separate tests.
In addition, it requires smaller samples and answers more questions about the disease.
Multiplex technology has been used for the last decade, but the diagnostic facility is the first veterinary diagnostic laboratory to use it to test for Lyme disease.
Different kinds of antibodies can be found in the body at different stages of infection. The new test can distinguish and measure these differences, giving more information about the timing of the disease.
The bacteria that cause Lyme disease are particularly difficult to detect, according to Wagner, because after infection they tend to hide where they can't be found. They bury in the joints of dogs, causing arthritis or lameness. Serious kidney disease has also been associated with Lyme infections in dogs.
In humans and horses, they also burrow into the nervous system, in the spine or the brain, causing pain, paralysis, or behavioural changes.
By the time such clinical signs appear, the bacteria are usually not in circulation anymore.
"Now we can distinguish between infection and vaccination and also between early and chronic infection stages," Wagner said.
"That was not possible before.
Lyme Disease Canine - News
Cornell University is now offering a new test for Lyme disease in horses and dogs. The new test reveals the infection history and simplifies the testing procedure. The bacteria that causes Lyme disease is Borrelia burgdorferi.

Veterinarian Mark Finkler is seeing more ticks on dogs this year, and more of his clients are testing positives for tick-borne diseases. "Lyme disease is what we're seeing right now," says Finkler. "We do see some ehrlichiosis and anaplasmosis.
A new test for Lyme disease in horses and dogs, developed by researchers at the Animal Health Diagnostic Center (AHDC) at the College of Veterinary Medicine at Cornell, will improve our understanding of the disease and pinpoint time of infection,

Late Thursday, Cornell University's Animal Health Diagnostic Laboratory announced a new test for Lyme Disease in dogs. The test looks for antibodies to Borrelia burgdorferi and has some significant improvements over previous tests for Lyme Disease.
In fact, new 2010 data collected in collaboration with IDEXX, ANTECH and Banfield Pet Hospitals show the distribution and prevalence of common parasitic diseases for dogs and cats like heartworm, Lyme disease, E. canis, roundworm, hookworm and whipworm
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Lyme Disease
“Our findings suggest for the first time that Borrelia burgdorferi, the bacteria that causes Lyme disease in humans, dogs and wild animals, a new strategy for the immune response of infected animals weaken, have developed,” said Professor Nicole Baumgarth, an authority on immune responses in the UC Davis Center for comparative medicine. The disease is mainly in the northeast United States Great Lakes region and to a lesser extent in Northern California. However, the tap of the Black-legged in the West, the main carrier of Lyme disease in the West of the USA, found in 56 of the 58 counties of California, according to the Ministry of public health in California.
Lyme DiseaseThe symptoms of Lyme disease are highly variable and possibly fever, headache, fatigue and a skin rash. If the infection is not treated, you can use the joints, the heart and the nervous system. They found that when mice infection with b. burgdorferi, these live parasites were built in the lymph nodes of the animals. Lymph glands responded with a strong and rapid accumulation of white blood cells, B cells, antibodies against the infection produce. Also, the presence of b. burgdorferi caused the destruction of the platform-independent of the lymph node that normally to function normally.
Lyme DiseaseWhile b-cells accumulate in large numbers and some antibodies specific against b. burgdorferi did, they weren’t “germinal centers,” the structures necessary for the generation of antibody responses very functional and long-lived. “Overall, these findings suggest that b. burgdorferi prevent the immune system to generate a response that is fully functional and which can persist and protection after repeated infections,” said Baumgarth. “Therefore, the study could explain why people who live in endemic areas can be repeatedly infected with this disease causing parasites.
Lyme Disease Canine - Bookshelf
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